Inhaltsangabe1. Discovery of Natural Products from Microalgae and Marine Organisms; F. Valeriote, R.E. Moore, G.M.L. Patterson, V.J. Paul, P.J. Scheuer, T. Corbett. 2. Discovery of Naturally Occurring Antitumor Agents; Ching-Jer Chang, C.L. Ashendel, R.L. Geahlen, J.L. McLaughlin. 3. Marine Invertebrates and Microbes as Sources of Potential Antitumor Compounds; A.L. Staley, J. Clardy. 4. Novel Strategies for the Discovery of Plant-Derived Anticancer Agents; G.A. Cordell, N.R. Farnsworth, C.W.W. Beecher, D.Doel Soejarto, A.D. Kinghorn, J.M. Pezzuto, M.E. Wall, M.C. Wani, R.R. Cobb, M.J. o'Neill, R.M. Tait, T.J.R. Harris. 5. A Strategy for Identifying Novel Inhibitors of DNA Topoisomerase I; S.M. Hecht, D.E. Berry, L.J. Mackenzie, E.A. Shultis, J.A. Chan. 6. Altromycins: a New Family of Antitumor Antibiotics-Discovery and Biological Evaluation; J.B. McAlpine, J.P. Karwowski, M. Jackson, G.M. Brill, S. Kadam, L. Shen, J.J. Clement, J. Alder, N.S. Burres. 7. Suppression of Human Melanoma Metastasis in SCID Mice with Antibodies to the EGF-Receptor; B.M. Mueller, R.A. Reisfeld. 8. Growth Factor and Oncogene Signalling as a Target for Anticancer Drug Development; G. Powis. 9. Nucleoside and Nucleotide Modulation of Oncogenic Expression: a New Approach to Cancer Chemotherapy; R.K. Robins, R.A. Finch, T.L. Avery. 10. Interferons in Cancer Therapy: from Clinical Trials to New Potentials in Anticancer Drug Discovery and Development; G.G. Steinmann, G.R. Adolf, G. Leitz. 11. Selection and Manipulation of Immunoglobulins for Radionuclide Delivery; Z. Steplewski, P. Curtis, J. Hainfield, R. Mease, S. Srivastava. 12. Microorganisms: Strategic Sources of Novel Anti-Tumor Agents; J.B. Tunac. 13. The Therapeutic Potential of Novel Pure Antiestrogens; A.E. Wakeling. 14. Preclinical Pharmacology and Phase I Clinical Trials of Taxotere (RP 56976, NSC 628503); M.-C. Bissery, H. Burris, R. Pazdur. 15. Bropriimine, a Small-Molecule Biological Response Modifier and an Effective Antitumor Agent; Li H. Li. 16. Determinants of Etoposide Cytotoxicity in vitro; R.B. Lock. 17. Screening for Anticancer Leads from Marine Organisms in a Mechanism-Based Drug Discovery Program; P. Crews, D.L. Slate, W.H> Gerwick, F.J. Schmitz, R. Schatzman, B. Strulovici, P. Cannon, L.M. Hunter.

1. Discovery of Natural Products from Microalgae and Marine Organisms; F. Valeriote, R.E. Moore, G.M.L. Patterson, V.J. Paul, P.J. Scheuer, T. Corbett. 2. Discovery of Naturally Occurring Antitumor Agents; Ching-Jer Chang, C.L. Ashendel, R.L. Geahlen, J.L. McLaughlin. 3. Marine Invertebrates and Microbes as Sources of Potential Antitumor Compounds; A.L. Staley, J. Clardy. 4. Novel Strategies for the Discovery of Plant-Derived Anticancer Agents; G.A. Cordell, N.R. Farnsworth, C.W.W. Beecher, D.Doel Soejarto, A.D. Kinghorn, J.M. Pezzuto, M.E. Wall, M.C. Wani, R.R. Cobb, M.J. o''Neill, R.M. Tait, T.J.R. Harris. 5. A Strategy for Identifying Novel Inhibitors of DNA Topoisomerase I; S.M. Hecht, D.E. Berry, L.J. Mackenzie, E.A. Shultis, J.A. Chan. 6. Altromycins: a New Family of Antitumor Antibiotics-Discovery and Biological Evaluation; J.B. McAlpine, J.P. Karwowski, M. Jackson, G.M. Brill, S. Kadam, L. Shen, J.J. Clement, J. Alder, N.S. Burres. 7. Suppression of Human Melanoma Metastasis in SCID Mice with Antibodies to the EGF-Receptor; B.M. Mueller, R.A. Reisfeld. 8. Growth Factor and Oncogene Signalling as a Target for Anticancer Drug Development; G. Powis. 9. Nucleoside and Nucleotide Modulation of Oncogenic Expression: a New Approach to Cancer Chemotherapy; R.K. Robins, R.A. Finch, T.L. Avery. 10. Interferons in Cancer Therapy: from Clinical Trials to New Potentials in Anticancer Drug Discovery and Development; G.G. Steinmann, G.R. Adolf, G. Leitz. 11. Selection and Manipulation of Immunoglobulins for Radionuclide Delivery; Z. Steplewski, P. Curtis, J. Hainfield, R. Mease, S. Srivastava. 12. Microorganisms: Strategic Sources of Novel Anti-Tumor Agents; J.B. Tunac. 13. The Therapeutic Potential of Novel Pure Antiestrogens; A.E. Wakeling. 14. Preclinical Pharmacology and Phase I Clinical Trials of Taxotere (RP 56976, NSC 628503); M.-C. Bissery, H. Burris, R. Pazdur. 15. Bropriimine, a Small-Molecule Biological Response Modifier and an Effective Antitumor Agent; Li H. Li. 16. Determinants of Etoposide Cytotoxicity in vitro; R.B. Lock. 17. Screening for Anticancer Leads from Marine Organisms in a Mechanism-Based Drug Discovery Program; P. Crews, D.L. Slate, W.H> Gerwick, F.J. Schmitz, R. Schatzman, B. Strulovici, P. Cannon, L.M. Hunter.